Obs! Registrering sker ej på vanligt sätt! Registreringsinstruktioner via denna länk.
Startat av affa, 2009-02-25, 13:57
CiteraVitamin D is an important regulator. It is produced not only by the UV-irradiated dermis, but also by activated macrophages, the hypercalcemia associated with sarcoidosis being attributable to production of the vitamin by macrophages in the active granulomas. The vitamin is a potent inhibitor of T-cell proliferation and of Th1 cytokine production.
CiteraSarcoidosis is a disease of unknown etiology affecting lymphoid tissue and involving the formation of chronic granulomas. A chronic inflammatory Th1 response to an infectious, environmental antigen is thought to be responsible.